Advances in DNA sequencing technology have made it possible for scientists all over the world to sequence complete microbial genomes rapidly and efficiently. Access to the DNA sequences of entire microbial genomes offers new opportunities to analyze and understand microorganism at the molecular level. Scientists are able to detect pathogens in biological tissues and study variations in gene expression in response to the pathogenic invasion. These responses help in designing novel approaches for microbial pathogen detection and drug development. Identification of certain microbial pathogens as etiologic agents responsible for chronic diseases is leading to new treatments and prevention strategies for these diseases.


Pathogen Detection Mechanism

Each species of pathogens carries with it a unique DNA or RNA signature that differentiate it from other organisms. One of the challenges is to develop this DNA signature for each microorganism of interest for rapid and specific detection.